GHK-Cu
$200.00
GHK-Cu – a copper peptide complex for research into wound healing, collagen synthesis, and regenerative signaling pathways.
✓ 99.9% Purity ✓ Lab Tested ✓ Based in USA
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Overview
GHK-Cu (Glycine-Histidine-Lysine Copper) is a naturally occurring tripeptide-copper complex first isolated from human plasma albumin by Loren Pickart in 1973. It is present in human plasma, saliva, and urine, and its plasma concentration declines significantly with age — a pattern that has made it a subject of interest in aging and regenerative research. GHK-Cu functions as a copper-chelating tripeptide that, upon binding cupric ions (Cu2+), modulates gene expression across a wide range of pathways including collagen synthesis, matrix metalloproteinase regulation, antioxidant defense (Nrf2), and angiogenesis. Over 3,000 human genes have been reported to be influenced by GHK-Cu in transcriptomic studies.
Specification
| CAS Number | 49557-75-7 (GHK); 89030-95-5 (GHK-Cu) |
| Chemical Name | Copper(II) complex of glycyl-L-histidyl-L-lysine; GHK-Cu |
| Peptide Type | Naturally occurring tripeptide-copper chelate; plasma peptide bioregulator |
| Sequence | H-Gly-His-Lys-OH · Cu2+ complex |
| Molecular Formula | C₁₄H₂₃CuN₆O₄ (GHK-Cu acetate) |
| Molecular Weight | 403.9 g/mol (GHK free tripeptide 340.38 g/mol) |
| Physical Appearance | Blue lyophilized powder (copper complex) |
| Purity | >99% per component (HPLC & Mass Spectrometry verified) |
| Verification Method | HPLC & MS |
| Container | Sterile sealed glass vial; 100 mg |
| Solubility | Soluble in sterile or bacteriostatic water; phosphate-buffered saline |
| Storage Conditions | 2–8°C; protect from light; long-term −20°C |
| Intended Use | Laboratory research use only (RUO) |
| COA Availability | Lot-specific COA provided per batch |
Potential Research Applications
GHK-Cu is studied across a broad range of regenerative, anti-aging, and gene-expression research models. Its ability to modulate thousands of genes through copper-mediated signaling makes it one of the most pleiotropic research peptides in the literature.
Skin Regeneration and Collagen Synthesis Research — Cell-culture and ex-vivo models examining collagen I and III synthesis, elastin production, fibroblast activation, and matrix metalloproteinase (MMP-2, MMP-9) regulation — key pathways in skin remodeling and wound healing research.
Wound Healing and Angiogenesis Studies — Rodent and cell-culture models documenting accelerated wound closure, enhanced keratinocyte migration, VEGF upregulation, and new capillary formation, with GHK-Cu identified as a potent pro-healing signal.
Nrf2-Mediated Antioxidant and Neuroprotection Research — Studies examining GHK-Cu’s activation of the Nrf2/ARE antioxidant pathway, superoxide dismutase (SOD) and catalase upregulation, and neuroprotective effects in oxidative stress models.
Transcriptomics and Gene Expression Modulation — Genome-wide expression studies identifying GHK-Cu as a broad modulator of genes involved in collagen metabolism, DNA repair, anti-inflammatory pathways, and stem cell activation, with applicability in aging and geroprotection research.
FAQ
Find answers to common questions about GHK-Cu, its research applications, documentation, and purchasing requirements.
Clinically Proven
Why Choose Telos
Every product we ship is engineered to remove variables and let your data speak for itself.
✧
cGMP Origin
Peptides are produced in ISO-9001 facilities that follow cGMP principles.
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Triple-Filtered
0.22 µm filtration and gamma irradiation safeguard sterility.
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3rd-Party Tested
Each lot is validated by a third-party lab for purity, identity, and endotoxin.
“For Research Only”
Frequently Asked Questions
✧ 1. What are Telos Health peptides used for?
All Telos Health products are sold for research use only. They are not intended for human consumption, therapeutic, or diagnostic use. Our peptides are designed exclusively for controlled laboratory research, educational studies, or analytical testing. Every product label and supporting document clearly reflects this compliance standard.
✦ 2. Who is eligible to purchase peptides?
Purchases are available to verified professionals, licensed clinics, educational institutions, and qualified research entities. Individuals may also purchase peptides for legitimate research or educational purposes, but all buyers must acknowledge and agree to Telos Wellness’s research-only terms prior to completing any order. We do not sell or endorse products for personal or medical use under any circumstance
♡ 3. How should peptides be handled and stored?
Peptides arrive as a lyophilized (freeze-dried) powder. For laboratory reconstitution, use only sterile bacteriostatic water or sterile saline (0.9 percent NaCl). Gently introduce the solvent and swirl—do not shake. Once reconstituted, store at 35°F to 45°F for short-term use, or at –4°F for long-term preservation. Protect vials from light and moisture, and avoid repeated freeze and thaw cycles to maintain stability.
⟡ 4. Why do peptide vials appear nearly empty?
Because peptides are measured in milligrams, the quantity often appears minimal or as a thin layer within the vial. This is completely normal for high-purity research peptides. Each vial undergoes precision weighing and purity testing using high-performance liquid chromatography (HPLC) and mass spectrometry to ensure the correct labeled amount is present.
✧ 5. What documentation and quality assurances come with each product?
Every peptide includes a Certificate of Analysis (COA) verifying its identity, purity (≥ 99 percent), and composition. Each batch is U.S. sourced and assembled under strict quality oversight and internal auditing. Full lot traceability, validated purity testing, and documentation accompany every shipment to ensure reproducibility, compliance, and scientific reliability.